약효검색서비스 항목
Cell based assay
| Assay | Detection |
|---|---|
|
Cell viability Reporter gene assay GPCR Cytokine |
ATP, MTS reduction, LDH release Single/Dual assay Ca2+, cAMP ELISA, HTRF |
Image analysis
Target activation, Cyto-cell Membrane Translocation, Cytoplasm-to-Nucleus Translocation, Colocalization, GPCR Signaling, etc
Disease/Target
| 질환 | 검색계 |
|---|---|
| 천식, 알러지 | PDE enzymes assay, β-Hexosaminidase, ROS/RNS assay*, β-adregergic receptor internalization assay(HCS), β-adregergic receptor calcium assay, CysLTR1 calcium assay |
| 당뇨 | GPR119 agonist assay, ER stress assay |
| 염증 | NF-kB translocation assay(HCS) , IL-8 HTRF assay, NF-kB Reporter gene assay, Cytokine ELISA, HO-1, COX-2 assay(HCS) |
| 미백 | Cell extracts tyrosinase assay, Cell-free(mushroom) tyrosinase assay, Melanin contents assay * |
| 암 | Cell cytotoxicity assasy, Growth inhibition assay(MTS, CCK-8), TCF/LEF reporter gene assay, IDO1, Arginase inhibition assay, IRAK4 kinase assay, Tankyrase-1 assay |
| 신경 | Acetylcholine esterase assay, β-amyloid aggregation aasay, Neurite outgrowth assay(HCS), Schwann cell differentiation assay(HCS), TRPA1 calcium assay, c-Jun assay(HCS) |
| 항산화 | DPPH assay, ROS/RNS assay(HCS), Keap1:Nrf2 inhibitor assay, ABTS assay |
| 통풍 | Xanthine oxidase assay |
| 주름개선 | Elastase assay, In vitro collagenase assay, Collagen synthesis assay* |
| 골다공증 | Osteoclastogenests assay(RAW 264.7)*, AR-S Assay(MC3T3-E1)* |
| 소양증 | Trypsin induced calcium assay |
| 통증 | TRPV1 calcium assay |
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